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1. estimated P2/P1 ratio
1. estimated P2/P1 ratio
The P2/P1 ratio compares the amplitude of the tidal wave (P2) to the percussion wave (P1) of the intracranial pressure waveform.
When P2 rises above P1, it signals reduced intracranial compliance and an elevated risk of intracranial hypertension.
P2/P1 > 1.4 : 90% specificity to assess risk of intracranial hypertension (IH)*
P2/P1 > 0.8 and < 1.2 : baseline threshold for healthy population*
P2/P1 < 0.8 : 92% sensitivity to rule out intracranial hypertension (IH)*
2. normalized Time-to-Peak
2. normalized Time-to-Peak
The normalized time to peak reflects the speed of intracranial pressure wave propagation—longer nTTP values indicate delayed pressure transmission and reduced intracranial compliance, often preceding intracranial hypertension.
nTTP > 0.3 : 92% specificity to assess risk of intracranial hypertension (IH)*
nTTP < 0.3 : baseline threshold for healthy population*
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